We’re thrilled to be participating in AMP 2024, and we have a few exciting activities lined up. If you can’t make either of our presentations, be sure to stop by booth 724 to learn about our NGS and qPCR solutions – designed to maximize performance with challenging clinically relevant samples.
- Increase coverage of rare variants with a DNA library prep that improves conversion of cfDNA from liquid biopsies
- Accurately identify both known and novel fusions with a whole transcriptome library prep that was designed to boost performance with low input and FFPE samples
- Reduce sequence artifacts and increase yields in FFPE DNA library preparation with an enzymatic fragmentation solution that enables scalable and automated processing
- Improve amplification from blood, urine, sputum, and bile-derived samples with an engineered polymerase and reverse transcriptase that exhibit extreme inhibitor tolerance
Presentations
Harnessing whole genome and transcriptome information to drive innovation in fusion and somatic variant detection
Pre-conference workshop with speakers from Nationwide Children’s Hospital and Inocras
Wednesday, November 20th, 2:00 PM – 2:50 PM
Room 111 & 112
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Clinically relevant sequencing applications require solutions that maximize the information output from low-input and degraded samples, such as cfDNA and FFPE. Watchmaker leverages enzyme engineering with multidimensional reaction optimization to develop NGS library preparation solutions that better maintain data integrity – minimizing bias and improving sequence accuracy to ultimately increase sensitivity.
Katherine Miller (Nationwide Children’s Hospital) will present on the value of whole transcriptome sequencing for sensitive fusion detection. Stephanie Ferguson (Inocras) will discuss target-enhanced whole genome sequencing to differentiate between tumor-specific alterations and inherited sequences to enhance somatic variant detection accuracy across diverse populations.
Maximizing data outputs and leveraging new data modalities to fuel clinical sequencing applications
Saturday, November 23rd, 9:30 AM – 10:00 AM
Innovation Spotlight Stage #2
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Clinical sequencing applications require solutions that maximize the information output from samples where template mass and quality are limited, such as cell free DNA and FFPE material. Accessing this information requires multiple enzymatic manipulations that are inefficient and can corrupt data. Watchmaker has paired novel enzyme engineering with multidimensional reaction optimization to develop DNA and RNA NGS library preparation solutions that better maintain data integrity – minimizing bias and improving sequence accuracy to ultimately increase sensitivity. Join us to learn about these advances, as well as our current development work in the space of DNA methylation, where there is large scope for improvement on DNA recovery, data quality, and ease of workflow.
Scientific Poster
Improved Gene Detection from Low-input FFPE Samples Using Total RNA Sequencing
Poster Number ST115
Saturday, November 23rd, 9:15 AM – 10:15 AM
Collaborator Posters
Comprehensive Genomic Profiling in Oncology: Clinical Applications of Target-Enhanced Whole-Genome Sequencing
Inocras
Poster Number G033
Saturday, November 23rd, 9:15 AM – 10:15 AM
Comparison of Library Preparation Kits for Next-Generation Sequencing on FFPE Samples
Inocras
Poster Number TT027
Saturday, November 23rd, 9:15 AM – 10:15 AM
Meet Our Team
We’d love to learn about your projects! Stop by Booth 724 or schedule a meeting to talk about our new products and early access programs.
Request a copy of our poster
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Visit the AMP 2024 Meeting Page for more information about the event.