RNA LIBRARY PREP SOLUTIONS

PRODUCTS

Sensitivity meets speed

Transcriptomics provides a snapshot of cellular activity at specific points in time and in response to environmental stimuli. It aims to characterize both protein-coding and non-coding transcripts (and the variation therein) and quantify their complex ebb and flow. This allows researchers to unravel biological mechanisms, detect and monitor cancer and other diseases, and validate biomarkers and drug responses.

There is a need for RNA library preparation solutions that are highly sensitive, scalable, robust with respect to performance with challenging clinically relevant sample types, such as FFPE and low inputs. Our portfolio delivers in all of these areas, enabling cutting edge research and applications in the transcriptomics space.

Key Highlights:

  • Increase sensitivity with FFPE and low-input samples
  • Generate high-quality libraries with a rapid, streamlined workflow
  • Improve automatability with fewer cleanups and handling steps
  • Discover the value of a reverse transcriptase engineered specifically for RNA sequencing

Select the workflow that fits your application needs

  Watchmaker RNA Library Prep Kit Watchmaker RNA Library Prep Kit with Polaris Depletion  
RNA input 0.25 to 100 ng 1 to 1000 ng
Library Prep Time < 3.5 hours (plus hybridization capture time) < 4.5 hours
RNA enrichment method None (typically used upstream of hybridization capture for targeted sequencing applications) Ribosomal and hemoglobin mRNA depletion
Species compatibility Any Human, mouse, and rat
Sample type compatibility Any
  • FFPE
  • Blood-derived
  • Tissue biopsies
  • Dried blood spots
  • Cell lines
  • Intact and partially degraded samples
Includes reagents for:
  • FFPE treatment
  • RNA library prep
  • Library amplification
  • rRNA/gobin depletion
  • FFPE treatment
  • RNA library prep
  • Library amplification
Types of RNA detected
  • Protein-coding (exonic; mRNA)
  • Long non-coding (lncRNA)
  • Protein-coding (exonic; mRNA)
  • Long non-coding (lncRNA)
Application fit
  • Targeted RNA-seq applications
  • Gene fusion detection
  • Gene expression analysis
  • Gene fusion detection
  • Isoform/alternative splicing analysis
  • Novel transcript discovery
  • Single nucleotide variant (SNV) detection
  • Long non-coding RNA-seq
  • Targeted RNA-seq applications
Learn more about:
Watchmaker RNA Library Prep Solutions

Watchmaker RNA Library Prep Kits

Generate stranded, high-complexity RNA-seq libraries in under 3.5 hours with inputs ranging from 0.25 to 100 ng total RNA
Watchmaker StellarScript HT Reverse Transcriptase Banner

Watchmaker RNA Library Prep Kits with Polaris Depletion

Highly sensitive, scalable, robust with respect to performance with challenging clinically relevant sample types, such as FFPE and low inputs